Articles (* peer-reviewed)
*1. Bolon BN, St. Omer VEV (1988). Brain monoamine levels in suckling mice following postnatal exposure to secalonic acid D via the dam's miIk. Toxicol Lett 44: 263-272.
*2. Bolon B, Calderwood Mays MB (1988). Conjugated avidin-peroxidase as a stain for mast cell tumors. Vet Pathol 25: 523-525.
*3. Bolon B, St. Omer VEV (1989). Behavioral and developmental effects in suckling mice following maternal exposure to the mycotoxin secalonic acid D. Pharmacol Biochem Behav 34: 229-236.
*4. Bolon B, Buergelt CD, Cooley AJ (1989). Abortion in two foals associated with Nocardia infection. Vet Pathol 26: 277-278.
*5. Bolon B, Greiner EC, Calderwood Mays MB (1989). Microscopic features of Sarcocystis falcatula in skeletal muscle from a Patagonian conure. Vet Pathol 26: 282-284.
*6. Bolon B, Harvey JW, Buergelt CD, Meyer DJ, Kaplan-Stein D (1989). Megakaryocytic leukemia in a dog. Vet Clin Pathol 18: 69-72.
7. Francis-Floyd R, Bolon B, Jacobson E (1989). Clinical management and pathology associated with chronic weight loss in the discus, Symphysodon sp. Proceedings, 20th Annual Meeting of the International Association of Aquatic Animal Medicine, San Antonio, TX, May 14-18. 20:3-7.
8. Specht D, Francis-Floyd R, Bolon B, Watson C (1989). Significance of intestinal parasitism in the mortality of domesticalIy-bred and imported angel fish, Pterophyllum scalare. Proceedings, 20th Annual Meeting of the International Association of Aquatic Animal Medicine, San Antonio, TX, May 14-18. 20:56-62.
*9. St. Omer VEV, Bolon B (1990). Secalonic acid D (SAD) mycotoxin affects ontogeny of brain catecholamines and swimming behavior in suckling mice. Neurotoxicol Teratol 12: 85-90.
*10. Hawthorne TAB, Bolon B, Meyer DJ (1990). Amyloidosis in a mare. J Am Vet Med Assoc 196: 323-325.
*11. Bolon B, Calderwood Mays MB, Hall BJ (1990). Characteristics of canine melanomas and relationship of histology and DNA ploidy to their biologic behavior. Vet Pathol 27: 96-102.
*12. Altman D, Bolon B, Meyer DJ, Homer B (1990) Cytologic features of meningioma in a dog. Vet Clin Pathol 18: 98-100.
*13. Bolon B, Buergelt CD (1990). A simple field necropsy technique for examination of the equine cervical spinal cord. Equine Prac 12: 26-29.
14. Bonnefoi M, Bolon B, Davenport C, Morgan KT (1990). Neurotoxicology at CIIT. CIIT Activities 10: 1-7.
15. Francis-Floyd R, Bolon B, Keefe T, Fraser W, Reed P, Watson C (1990). A suspected new viral disease of angel fish. Proceedings, 21st Annual Meeting of the International Association of Aquatic Animal Medicine, Vancouver, British Columbia, May 13-17. 21: 33-37.
*16. Peele DB, Allison SD, Bolon B, Prah JD, Jensen KF, Morgan KT (1991). Functional deficits produced by 3-methylindole-induced olfactory mucosal damage revealed by a simple olfactory learning task. Toxicol Appl Pharmacol 107: 191-202.
*17. Bolon B, Bonnefoi M, Roberts K, Marshall M, Morgan KT (1991). Toxic interactions in the rat nose: Pollutants from soiled bedding and methyl bromide. Toxicol Pathol 19: 571-578, 1991.
*18. Bolon B, St. Omer VEV (1992). Biochemical correlates for behavioral deficits induced by secalonic acid D in developing mice. Neurosci Biobehav Rev 16: 171-175.
*19. Beale KM, Altman D, Clemmons RR, Bolon B (1992). Systemic toxicosis associated with azathioprine administration in domestic cats. Am J Vet Res 53: 1236-1240.
20. Beale KM, Bolon B (1992). Canine cutaneous lymphosarcoma: Epitheliotropic and non-epitheliotropic, a retrospective study. Proceedings of the 2nd World Congress of Veterinary Dermatology, Montreal, May 11-16.
*21. Robertson SA, Green SL, Carter SW, Bolon B, Brown MP, Shields RP (1992). Postanesthetic recumbency associated with hyperkalemic periodic paralysis in a quarter horse. J Am Vet Med Assoc 201: 1209-1212.
*22. Francis-Floyd R, Bolon B, Fraser W, Reed P (1993). Lip fibromas associated with retrovirus-like particles in angel fish. J Am Vet Med Assoc 202: 427-429.
*23. Fraser WA, Keefe TJ, Bolon B (1993). Isolation of an iridovirus from farm-raised gouramis (Trichogaster trichopterus) with fatal disease. J Vet Diag Invest 5: 250-253.
*24. Dorman DC, Dye JA, Nassise MP, Ekuta J, Bolon B, Medinsky MA (1993). Acute methanol toxicity in minipigs. Fundam Appl Toxicol 20: 341-347.
*25. Francis-Floyd R, Reed P, Bolon B, Estes J, McKinney S (1993). An epizootic of Edwardsiella tarda in largemouth bass (Micropterus salmoides). J Wildlife Dis 29: 334-336.
*26. Dorman DC, Bolon B, Morgan KT (1993). The toxic effects of formate in dissociated primary neural cell cultures. Toxicol Appl Pharmacol 122: 265-272.
*27. Bolon B, Dorman DC, Bonnefoi MS, Randall H, Morgan KT (1993). Histopathologic approaches to chemical toxicity using primary cultures of dissociated neural cells grown in chamber slides. Toxicol Pathol 21: 465-479.
*28. Bolon B, Dorman DC, Welsch F (1993). Phase-specific developmental toxicity in mice following maternal methanol inhalation. Fundam Appl Toxicol 21: 508-519.
*29. Bolon B, Welsch F, Morgan KT (1994). Methanol-induced neural tube defects in mice: Pathogenesis during neurulation. Teratology 49: 497-517.
*30. Fox LE, King RR, Calderwood Mays M, Cooley AJ, Meyer D, Bolon B (1994). Primary pulmonary osteosarcoma in a dog. J Small Anim Prac 35: 329-332.
*31. Dorman DC, Bolon B, Struve MF, LaPerle KMD, Wong BA, Elswick B, Welsch F (1995). The role of formate in methanol-induced exencephaly in CD-1 mice. Teratology 52: 30-40.
*32. Dorman DC, Wong BA, Struve MF, James RA, LaPerle KMD, Marshall M, Bolon B (1996) Development of a mouse whole-body exposure system from a directed-flow, rat nose-only system. Inhal Toxicol 8: 107-120.
*33. Bolon B, Dunn C, Goldsworthy TL (1996). Region-specific DNA synthesis in brains of F344 rats following a six-day bromodeoxyuridine infusion. Cell Prolif 29:505-511.
*34. Terry KK, Stedman DB, Bolon B, Welsch F (1997). Effect of 2-methoxyethanol on mouse neurulation. Teratology 54: 219-229.
*35. James SJ, Pogribna M, Miller BJ, Bolon B, Muskhelishvilli L (1997). Characterization of the cellular response to silicone implants in rats: Implications for foreign body carcinogenesis. Biomaterials 18: 667-675.
*36. Bucci TJ, Bolon B, Warbritton, AR, Chen JJ, Heindel JJ (1997). Influence of sampling on the reproducibility of ovarian follicle counts in mouse toxicity studies. Repro Toxicol 11: 689-696.
*37. Bolon B, Bucci TJ, Warbritton, AR, Chen JJ, Mattison DR, Heindel JJ (1997). Differential follicle counts as a screen for ovarian toxicity in mice: Results from continuous breeding bioassays for fifteen chemicals. Fundam Appl Toxicol 39: 1-10.
*38. Francis-Floyd R, Reed P, Gibbs P, Shotts E, Bolon B, Coleman W, Klinger R (1998). Isolation of Acholeplasma laidlawii from centrarchids in a central Florida lake. J Aquat Anim Health 10: 252-258.
*39. Hu MC-T, Wang Y, Qiu WR, Hill D, Ring BD, Bolon B, DeRose M, Simonet WS, Arakawa T, Danilenko DM (1998). FGF-18, a novel member of the fibroblast growth factor family that stimulates hepatic and intestinal proliferation. Mol Cell Biol 18: 6063-6074.
*40. Min H, Danilenko DM, Scully SA, Bolon B, Ring BD, Tarpley JE, DeRose M, Simonet WS (1998). FGF-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev 12: 3156-3161.
*41. LaBorde JB, Wall KS, Bolon B, Kumpe TS, Patton R, Zheng Q, Kodell R, Young JF (1999). Haematology and serum chemistry parameters of the pregnant rat. Lab Anim 33: 275-287.
*42. Kong Y-Y, Feige U, Sarosi I, Bolon B, Tafuri A, Morony S, Capparelli C, Li J, Elliott R, McCabe S, Wong T, Campagnuolo G, Moran E, Bogoch ER, Van G, Nguyen LT, Ohashi PS, Lacey DL, Fish E, Boyle WJ, Penninger JM (1999). Activated T cells regulate bone loss and joint destruction in arthritis through osteoprotegerin ligand. Nature 402: 304-309.
*43. Pauken CM, LaBorde JB, Bolon B (1999). Retinoic acid acts during peri-implantational development to alter axial and brain formation. Anat Embryol 200: 645-655.
*44. Bolon B (2000). Comparative and correlative neuroanatomy for the toxicologic pathologist. Toxicol Pathol 28: 6-27. [Companion paper to invited presentation.]
*45. Sasaki T, Irie-Sasaki J, Jones RG, Oliveira-dos-Santos AJ, Stanfield WL, Bolon B, Wakeham A, Itie A, Bouchard D, Kozieradzki I, Joza N, Mak TW, Ohashi PS, Suzuki A, Penninger JM (2000). Function of PI3Kg in thymocyte development, T cell activation and neutrophil migration. Science 287: 1040-1046.
*46. Genter MB, Burman DM, Dingeldein MW, Clough I, Bolon B (2000). Evolution of alachlor-induced nasal neoplasms in the Long-Evans rat. Toxicol Pathol 28: 770-781.
*47. Feige U, Hu Y-L, Gasser J, Campagnuolo G, Munyakazi L, Bolon B (2000). Anti-interleukin-1 and anti-tumor necrosis factor-a synergistically inhibit adjuvant arthritis in Lewis rats. Cell Mol Life Sci 57: 1457-1470.
*48. Bolon B, Carter C, Daris M, Morony S, Capparelli C, Hsieh A, Mao M, Kostenuik P, Dunstan CR, Lacey DL, Sheng J (2001). Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis. Mol Ther 3: 197-205. [Featured article on cover]
*49. Luo Y, Bolon B, Kahn S, Bennett BD, Babu-Khan S, Denis P, Fan W, Kha H, Zhang J, Gong Y, Martin L, Louis J-C, Yan Q, Richards WG, Citron M, Vassar R (2001). Mice deficient in BACE1, the Alzheimer’s b-secretase, have normal phenotype and abolished b-amyloid generation. Nature Neurosci 4: 231-232.
*50. Backman SA, Stambolic V, Suzuki A, Haight J, Pretorius J, Tsao M-S, Shannon P, Bolon B, Ivy GO, Mak TW (2001). Targeted disruption of PTEN in mouse brain causes seizures and ataxia associated with neuronal cell size defects resembling Lhermitte-Duclos disease. Nature Genet 29: 396-403.
*51. Smith JC, Bolon B (2002). Atmospheric waste isoflurane concentrations using conventional equipment and rat anesthesia protocols. Contemp Topics Lab Anim Sci 41: 10-17. [Featured article on cover]
*52. Bolon B, Galbreath EJ (2002). Use of genetically engineered mice in drug discovery and development: Wielding Occam’s razor to prune the product portfolio. Int J Toxicol 21: 55-64. [Companion paper to invited presentation by BB]
*53. Campagnuolo G,1 Bolon B,1 Feige U (2002). Kinetics of bone protection by recombinant osteoprotegerin (OPG) therapy in Lewis rats with adjuvant arthritis. Arthritis Rheum 46: 1926-1936. [1Equal contributors]
*54. Coxon A,1 Bolon B,1 Estrada S, Kaufman S, Scully S, Rattan A, Duryea D, Hu Y-L, Rex K, Pacheco E, Zack D, Feige F (2002). Inhibition of IL-1 but not TNF inhibits neovascularization in rat models of corneal angiogenesis and adjuvant arthritis. Arthritis Rheum 46: 2604-2612. [1Equal contributors]
*55. Bolon B,1 Campagnuolo G,1 Feige U (2002). Duration of bone protection afforded by a single injection of recombinant osteoprotegerin (OPG) in male Lewis rats with adjuvant-induced arthritis. Cell Mol Life Sci 59: 1569-1576. [1Equal contributors]
*56. Bolon B, Shalhoub V, Kostenuik PJ, Campagnuolo G, Morony S, Boyle WJ, Zack D, Feige U (2002). Osteoprotegerin (OPG): an endogenous anti-osteoclast factor for protecting bone in rheumatoid arthritis. Arthritis Rheum 46: 3121-3135. [Invited review]
*57. Genter MB, Burman D, Bolon B (2002). Progression of alachlor-induced olfactory mucosal tumors in rats. Int J Exp Pathol 83: 303-307.
*58. Campagnuolo G,1 Bolon B,1 Zhu L, Duryea D, Feige U, Zack D (2003). IL-1b and TNF-a produce divergent acute inflammatory and skeletal lesions in the knees of Lewis rats. Ann NY Acad Sci 987: 295-298. [1Equal contributors]
*59. Smith JC, Bolon B (2003). Comparison of three commercially available activated charcoal canisters for passive scavenging of waste isoflurane during conventional rodent anesthesia. Contemp Topics Lab Anim Sci 42: 10-15. [Featured article on cover]
*60. Luo Y, Bolon B, D’Amore MA, Fitzpatrick D, Liu H, Zhang J, Yan Q, Vassar R, Citron M (2003). BACE1 (b-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time. Neurobiol Dis 14: 81-88.
*61. Schett G, Redlich K, Hayer S, Zwerina J, Bolon B, Dunstan C, Görtz B, Schulz A, Bergmeister H, Kollias G, Steiner G, Smolen JS (2003). Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice. Arthritis Rheum 48: 2042-2051.
*62. Discenza MT, He SJ, Lee TH, Chu LL, Bolon B, Goodyer P, Eccles M, Pelletier M (2003). WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2. Oncogene 22: 8145-8155.
*63. Bolon B, Morony S, Cheng Y, Hu Y-L, Feige U (2004). Osteoclast numbers in Lewis rats with adjuvant-induced arthritis: Identification of preferred sites and parameters for rapid quantitative analysis. Vet Pathol 41: 30-36.
*64. Smith JC, Corbin TJ, McCabe JG, Bolon B (2004). Isoflurane with morphine is a favorable anesthetic regimen for embryo transfer in production of transgenic rats. Lab Anim 38: 38-43.
*65. Nakayama N, Han CE, Cam L, Lee JI, Pretorius J, Fisher S, Rosenfeld R, Scully S, Nishinakamura R, Duryea D, Van G, Bolon B, Yokota T, Zhang K (2004). A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage. Development 131: 229-240.
*66. Kostenuik P,1 Bolon B,1 Morony S, Daris M, Geng Z, Carter C, Sheng J (2004). Gene therapy with human recombinant osteoprotegerin (OPG) reverses established osteopenia in ovariectomized mice. Bone 34:656-664 [1Equal contributors]
*67. Bolon B, Jing S, Asuncion F, Scully S, Pisegna M, Van G, Hu Z, Yu YB, Min H, Wild K, Rosenfeld RD, Tarpley J, Carnahan J, Duryea D, Hill D, Kaufman S, Yan X-Q, Juan T, Christensen K, McCabe J, Simonet WS (2004). The candidate neuroprotective agent artemin induces autonomic neural dysplasia without preventing peripheral nerve dysfunction. Toxicol Pathol 32: 275-294.
*68. Bolon B, Campagnuolo G, Zhu L, Duryea D, Zack D, Feige U (2004). Interleukin-1b and tumor necrosis factor-a produce distinct, time-dependent patterns of acute arthritis in the rat knee. Vet Pathol 41: 235-243.
*69. Smith JC, Bolon B (2004). Endotracheal tubes vs. laryngeal mask airways in rabbit inhalation anesthesia: ease of use and waste gas emissions. Contemp Topics Lab Anim Sci 45: 22-25.
*70. Bolon B (2004). Genetically engineered animals in drug discovery and development: A maturing resource for toxicologic research. Basic Clin Pharmacol Toxicol 95: 154-161. [Invited review]
71. Bolon B (2004). Immune-mediated arthritis: Molecular mechanisms and comparative pathology. Proceedings of the 55th Annual Meeting of the American College of Veterinary Pathologists, Orlando, FL, November 13-17, pp. 270-273. [Brief to accompany invited presentation]
*72. Schett G, Middleton S, Bolon B, Stolina M, Brown H, Zhu L, Pretorius J, Zack DJ, Kostenuik P, Feige U (2005). Additive bone-protective effects of anabolic treatment when used in conjunction with RANKL and tumor necrosis factor inhibition in two rat arthritis models. Arthritis Rheum 52: 1604-1611
*73. Schett G, Stolina M, Bolon B, Middleton S, Adlam M, Brown H, Zhu L, Feige U, Zack DJ (2005). Analysis of the kinetics of osteoclastogenesis in arthritic rats. Arthritis Rheum 52: 3192-3201.
*74. Genter MB, Warner BM, Krell H-W, Bolon B (2005). Reduction of alachlor-Induced olfactory mucosal neoplasms by the matrix metalloproteinase inhibitor Ro-28-2653. Toxicol Pathol 33:593-599.
*75. Stolina M, Adamu S, Ominsky M, Dwyer D, Asuncion F, Geng Z, Middleton S, Brown H, Pretorius J, Schett G, Bolon B, Feige U, Zack D, Kostenuik PJ (2005). RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis. J Bone Min Res 20: 1756-1765.
*76. Bolon B (2006). Internet resources for phenotyping engineered rodents. ILAR J 47: 163-171. [Invited review]
*77. Smith JC, Bolon B (2006). Comparative isoflurane leakage from conventional facemasks on a non-rebreathing rodent anesthesia system. Lab Anim 40: 200-209.
*78. Bolon B, Garman R, Jensen K, Krinke G, Stuart B (2006). A ‘best practices’ approach to neuropathologic assessment in developmental neurotoxicity testing – for today. Toxicol Pathol 34: 296-313. [STP position paper]
*79. Li J, Sarosi I, Cattley RC, Pretorious J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards, WG (2006). Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone 39: 754-766.
*80 Holst CR, Bou-Reslan H, Gore BB, Wong K, Grant D, Chalasani S, Carano RA, Frantz G, Tessier-Lavigne M, Bolon B, French DM, Ashkenazi A. Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. PLoS ONE 2: e575.
*81. Stolina M, Dwyer D, Ominsky MS, Corbin T, Van G, Bolon B, Sarosi I, McCabe J, Zack DJ, Kostenuik P (2007). Continuous RANKL inhibition in osteoprotegerin transgenic mice and rats suppresses bone resorption without impairing lymphorganogenesis or functional immune responses. J Immunol 179: 7497-7505.
*82 Bolon B. Whole mount enzyme histochemistry as a rapid screen at necropsy for expression of ß-galactosidase (LacZ)-bearing transgenes: Considerations for separating specific LacZ activity from non-specific (endogenous) galactosidase activity. Toxicol Pathol (in press).
